Ethylenic and allenic phosphonate derivatives of purines

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Phosphorus containing other than solely as part of an...

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544244, 544265, 514262, 558187, 558189, A61K 31675, C07F 96512

Patent

active

059226960

ABSTRACT:
Disclosed are novel unsaturated phosphonate derivatives of certain purines or pyrimidines useful as antiviral agents, methods useful for their preparation and use of these compounds as antiviral agents effective against DNA viruses, retroviruses and viruses involved in tumor formation.

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patent: 5532225 (1996-07-01), Reist et al.
patent: 5817647 (1998-10-01), Casara et al.
J. Org. Chem. (1992) vol. 57, No. 8, pp. 2320-2327.
J. Med. Chem. (1993) vol. 36, No. 10, pp. 1343-1355.

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