Ethylenedicysteine (EC)-drug conjugates, compositions and...

Drug – bio-affecting and body treating compositions – In vivo diagnosis or in vivo testing – X-ray contrast imaging agent

Reexamination Certificate

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C424S001110, C424S001650, C424S001690, C424S009100

Reexamination Certificate

active

10672763

ABSTRACT:
The invention provides, in a general sense, a new labeling strategy employing99mTc chelated with ethylenedicysteine (EC). EC is conjugated with a variety of ligands and chelated to99mTc for use as an imaging agent for tissue-specific diseases. The drug conjugates of the invention may also be used as a prognostic tool or as a tool to deliver therapeutics to specific sites within a mammalian body. Kits for use in tissue-specific disease imaging are also provided.

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