Ethylenediamine monoamides

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...

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514346, 514352, 514365, 514374, 546291, 546308, 546309, 546323, 548200, 548248, 548235, 544406, 549 72, 549487, A61K 3144, C07D21381, C07D26118, C07D27756

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active

047645229

ABSTRACT:
Compounds of the formula ##STR1## wherein R is an aromatic, 5- or 6-membered heterocyclic residue, as described herein, and their pharmaceutically usable acid addition salts are described. These compounds have interesting monoamine oxidase inhibiting properties with low toxicity and can accordingly be used for the treatment of depressive states and parkinsonism.

REFERENCES:
patent: 4034106 (1977-07-01), Smith
CA 99:157898r Marsham et al.; 1983.
CA 99:212539b Barlow et al.; 1983.
CA 71 81421d Cragoe et al.; 1909.
CA 74;53846g Gragoe et al.; 1971.
CA 41:1947,1325f
CA 96:162116b 1982.
CA 96:161957q Sitzius et al.; 1982.
CA 86:135937e Schubert et al.; 1977.
CA 97:182347b Large et al.; 1982.
CA 84:135281x Smith; 1976.

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