Ethylene oxide process dosimeter

Chemistry: analytical and immunological testing – Process or composition for sterility or package integrity test

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422 56, 422 87, 436 93, 436902, G01N 2178

Patent

active

044368194

ABSTRACT:
A device for chemically quantifying ethylene oxide exposure is disclosed as are methods for its use. The device comprises an ethylene oxide-permeable layer exhibiting unusual non-Fickian EO transport and containing a controlled amount of compound which forms a colored species upon reaction with ethylene oxide. Optionally, the response layer is laminated or otherwise joined with a support layer. The device can be used to quantify in industry accepted units of time and concentration sterilization dosages of ethylene oxide.

REFERENCES:
patent: 3627469 (1971-12-01), Cheng
patent: 3852034 (1974-12-01), Gunther
patent: 4094642 (1978-06-01), Sumimoto et al.
patent: 4195056 (1980-03-01), Patel
Alfrey, Jr. et al., Journal of Polymer Science: Part C No. 12, pp. 249-261, (1966), "Diffusion in Glassy Polymers".

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