Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Patent
1996-10-30
1997-10-14
Ramsuer, Robert W.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
548444, A61K 3140, C07D20988
Patent
active
056773285
ABSTRACT:
Novel substituted carbazole compounds of Formula I are active as melatonergic agents: ##STR1## wherein: R.sub.1 is C(O)R.sub.3 or SO.sub.2 R.sub.4 ;
REFERENCES:
patent: 3975398 (1976-08-01), Werner et al.
patent: 5206377 (1993-04-01), McAfee
Ebisawa, et al., "Expression Cloning of a High-Affinity Melatonin Receptor From Xenopus Dermal Melanophores" Proc. Natl. Acad. Sci. 91: pp. 6133-6137.
Cassone, et al., "Dose-Dependent Entrainment of Rat Circadian Rhythms by Daily Injection of Melatonin" J. Biol. Rhythms 1: pp.219-229 (1986).
Arendt, et al., "Alleviation of Jet Lag by Melatonin: Preliminary Results of Controlled Double Blind Trail" Br. Med. J. 292: 1170 (1986).
Stamm, et al., "Amidoethylierung des Fluorens mit N-Acylaziridinen. Umlagerung eines N-Acylaziridins zu einem 2-Pyrrolidon" Chem. Ber. 111: pp. 2665-2666 (1978).
Bruce Marc A.
Poindexter Graham S.
Takaki Katherine S.
Watson Brett T.
Yevich Joseph P.
Algieri Aldo A.
Bristol--Myers Squibb Company
Ramsuer Robert W.
LandOfFree
Ethylamino carbazole melatonergic agents does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Ethylamino carbazole melatonergic agents, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Ethylamino carbazole melatonergic agents will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-1555642