Ethoxycarbonyloxy ethyl esters of non-steroidal anti-inflammator

Details Ethoxycarbonyloxy ethyl esters of non-steroidal anti-inflammator Ethoxycarbonyloxy ethyl esters of non-steroidal anti-inflammator

1986-02-12

1989-07-25

Springer, David B.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

514423, 514512, 548500, 548539, 558275, 558276, C07D20928, C07D207333, C07C 6996, A61K 31405, A61K 3140, A61K 31265

Patent

active

048514268

ABSTRACT:
Novel esters of the general formula ##STR1## in which ##STR2## is the acyl residue of a non-steroidal anti-inflammatory compound containing a carboxylic acid function. The novel esters are prepared by reacting an acide R--COOH when R is as above, with 1-haloethyl ethyl carbonate. There are also provided pharmaceutical compositions containing any of the said novel esters.

REFERENCES:
patent: 3412131 (1968-11-01), Swintosky
patent: 3646201 (1972-02-01), Kallianos et al.
patent: 4412994 (1983-11-01), Sloan et al.
patent: 4426391 (1984-01-01), Alexander et al.
patent: 4483867 (1984-11-01), Svehn et al.
patent: 4542158 (1985-09-01), Dorn

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