Drug – bio-affecting and body treating compositions – Antigen – epitope – or other immunospecific immunoeffector – Bacterium or component thereof or substance produced by said...
Patent
1981-11-16
1983-09-27
Coughlan, Jr., Paul M.
Drug, bio-affecting and body treating compositions
Antigen, epitope, or other immunospecific immunoeffector
Bacterium or component thereof or substance produced by said...
544336, A61K 31495, C07D24112
Patent
active
044069014
ABSTRACT:
Ethers of substituted hydroxymethylpyrazines, such as, for instance, the compound 2-methoxymethyl-5-methylpyrazine-4-oxide. The compounds exhibit elevated lipid-lowering activity, especially anti-lipolytic activity (decrease of plasma-free fatty acids), triglyceride-lowering activity, cholesterol-lowering activity, and plasma-phospholipid-lowering activity.
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patent: 4051245 (1977-09-01), Ambrogi et al.
patent: 4267327 (1981-05-01), Cozzi et al.
Taylor, Harold, "2-Pyrazinemethanols", Chem. Abst. 84: 59572(a), (1976).
Bertone Leone
Cozzi Paolo
Lovisolo Pier P.
Pillan Antonio
Coughlan, Jr. Paul M.
Farmitalia Carlo Erba S.p.A.
Hendricks G.
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