Ethers

Details Ethers Ethers

1988-08-01

1990-05-29

Daus, Donald G.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

544264, 544316, 544408, 544238, 546108, 546109, 546126, 546133, 546134, 546138, 514253, 514256, 514305, 514306, 514307, A61K 31435

Patent

active

049296256

ABSTRACT:
Novel ethers of formula ##STR1## their heteroaromatic N-oxides, and the pharmaceutically acceptable acid additions of the compounds of formula (I) and their N-oxides possess 5-HT.sub.3 -antagonistic activity. In the formula ##STR2## represents an optionally substituted heteroaryl group containing a hetero atom X and --B represents a saturated azabicyclic ring such as quinuclidyl or tropanyl.

REFERENCES:
patent: 2640829 (1953-06-01), Wilson et al.
patent: 3716544 (1973-02-01), Gadient
patent: 4643995 (1987-02-01), Engel et al.
Chem. Abstr., vol. 57, col. 9805c, (1962).

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