Ethanocarbazole derivatives and antidepressant compositions

Details Ethanocarbazole derivatives and antidepressant compositions Ethanocarbazole derivatives and antidepressant compositions

1980-12-19

1981-12-08

Jiles, Henry R.

Drug, bio-affecting and body treating compositions

Antigen, epitope, or other immunospecific immunoeffector

Bacterium or component thereof or substance produced by said...

4242484, 424250, 424267, 424274, 544 60, 544142, 544372, 546200, 260315, A61K 3154, A61K 3140, C07D20986, C07D20988

Patent

active

043047726

ABSTRACT:
Herein is disclosed ethanocarbazole derivatives, acid addition salts thereof, processes for their preparation, methods of using the derivatives and pharmaceutical compositions of the derivatives. The derivatives are useful for treating depression in a mammal and are represented by the following formula ##STR1## in which R.sup.1 is hydrogen or lower alkyl, R.sup.2 and R.sup.3 each is hydrogen or lower alkyl or R.sup.2 and R.sup.3 together with the nitrogen atom form a 1-pyrrolidinyl, 1-piperidinyl, 1-piperazinyl, 4-morpholinyl or 4-thiomorpholinyl ring, and m is an integer from 0 to 3.

REFERENCES:
Derwent Publications Ltd., Farmdoc 49955C, DT 28549 41, 10-7-80 (Germany).
R. Robinson and J. E. Saxton, J. Chem. Soc., 2596 (1953).
H. Plieninger et al., Chem. Abstr., 60 11997c (1964) for Chem. Ber., 97,667 (1964).

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