Estrogenic extracts of Morus alba and uses thereof

Details Estrogenic extracts of Morus alba and uses thereof Estrogenic extracts of Morus alba and uses thereof

2005-12-09

2010-10-19

Tate, Christopher R (Department: 1655)

Drug, bio-affecting and body treating compositions

Plant material or plant extract of undetermined constitution...

Containing or obtained from a leaf

C424S769000, C424S725000, C424S439000, C424S400000

Reexamination Certificate

active

07815949

ABSTRACT:
Extracts of various species of the Moraceae family have estrogenic properties. For example, aqueous and ethanolic extracts ofMorus albaL. species possess estrogenic properties in both ERα+ and ERβ+ cells. These estrogenic effect include estrogen response element (ERE) stimulation as well as tumor necrosis factor (TNF) repression. Methods are provided for treating climacteric symptoms, breast and/or uterine cancer, and osteoporosis.

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Supplemental EP Search Report mailed Apr. 14, 2008.
Ray et al., “Histological study on the effect of phytoestrogen on uterus and ovary of animal,” 19660101, Indian Science Congress Association Proceedings 53(nr3):461, ISSN 0085-1817.
EP 05853308.4 Official Action mailed Jul. 13, 2010.

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