Estrogenic compounds as anti-mitotic agents

Details Estrogenic compounds as anti-mitotic agents Estrogenic compounds as anti-mitotic agents

2006-07-25

2006-07-25

Witherspoon, Sikarl A. (Department: 1621)

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Ester doai

C514S559000, C514S661000, C514S719000, C514S730000, C514S738000

Reexamination Certificate

active

07081477

ABSTRACT:
The application discloses methods of treating mammalian diseases characterized by abnormal cell mitosis by administering estradiol derivatives including those comprising colchicine or combretastatin A-4 structural motifs of the general formulae found below in a dosage sufficient to inhibit cell mitosis. The application discloses novel compounds used in the methods.

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