Estrogenic compounds as anti-mitotic agents

Details Estrogenic compounds as anti-mitotic agents Estrogenic compounds as anti-mitotic agents

2006-09-19

2006-09-19

Badio, Barbara P. (Department: 1616)

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Cyclopentanohydrophenanthrene ring system doai

C514S824000, C514S825000, C514S863000, C514S886000, C514S899000, C514S912000, C514S914000

Reexamination Certificate

active

07109187

ABSTRACT:
The application discloses methods of treating mammalian diseases characterized by abnormal cell mitosis by administering estradiol derivatives including those comprising colchicine or combretastatin A-4 structural motifs of the general formulae found below in a dosage sufficient to inhibit cell mitosis. The application discloses novel compounds used in the methods.

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