Organic compounds -- part of the class 532-570 series – Organic compounds – Heterocyclic carbon compounds containing a hetero ring...
Reexamination Certificate
2011-03-08
2011-03-08
Chandrakumar, Nizal S (Department: 1625)
Organic compounds -- part of the class 532-570 series
Organic compounds
Heterocyclic carbon compounds containing a hetero ring...
Reexamination Certificate
active
07902384
ABSTRACT:
The present invention relates to compounds having estrogenic activity selected from the group consisting of Loliolide, (4S,6S)-4-Hydroxy-6-nonadecyl-tetrahydro-pyran-2-one, (4R,6S)-4-Hydroxy-6-nonadecyl-tetrahydro-pyran-2-one and analogues thereof. The compounds of the present invention are selective estrogen receptor modulator, which can selectively activate ERβ and simultaneously express high estrogenic activity, and also can be applied as medical or food compositions to improve estrogen deficiency-related symptoms.
REFERENCES:
patent: 5292898 (1994-03-01), Hammann et al.
Kuo et al. STN Accession No. 2002, Document No. 138:86521, Abstract of Journal of the Chinese Chemical Society (Taipei, Taiwan) (2002), 49(3),427-431.
Hong Yong-Han
Hsu Chin
Huang Ching-Jang
Kuo Yueh-Hsiung
Lin Bi-Fong
Chandrakumar Nizal S
King Anthony
National Taiwan University
WPAT, P.C.
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