Estrogen receptor α regulated gene expression, related...

Combinatorial chemistry technology: method – library – apparatus – Library – per se

Reexamination Certificate

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C435S006120, C536S023100, C536S024310, C536S023500, C506S009000

Reexamination Certificate

active

07371207

ABSTRACT:
A plurality of genes modulated by estrogen or other agents, such as hormones or combinations of hormones, in various types of tissue is described. One embodiment of the disclosure relates to a plurality of genes, which demonstrates certain patterns of expression differing qualitatively or quantitatively, with and without exposure to estrogen and/or other hormone compositions. Methods of using these genes in identifying candidate agents that exert at least some of the biological effects of estrogen and/or other hormone, and pharmaceuticals and related therapies also is disclosed. The use of the plurality of genes in methods of monitoring, in gene chips and in kits also is disclosed.

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