Estrogen metabolites for lowering intraocular pressure

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Cyclopentanohydrophenanthrene ring system doai

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514170, 514913, A61K 3133, A61K 3156

Patent

active

055211682

ABSTRACT:
Methods for lowering and controlling intraocular pressure using estrogen metabolites are disclosed.

REFERENCES:
patent: 4876250 (1989-10-01), Clark
patent: 5371078 (1994-12-01), Clark et al.
Treister, et al., Intraocular Pressure and Outflow Facility, Arch. Ophthal., 83, 311-318 (Mar., 1970).
Meyer, et al., Influence of Norethynodrel With Mestranol on Intraocular Pressure in Glaucoma, Arch. Ophthal., 75, 771-773 (Jun., 1966).
Fotsis, et al., The Endogenous Oestrogen Metabolite 2-Methoxyestradiol Inhibits Angiogenesis and Suppresses Tumour Growth, Letters to Nature, 368, 237-239 (Mar. 17, 1994).

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