Estrogen-containing active substance plaster

Drug – bio-affecting and body treating compositions – Preparations characterized by special physical form – Web – sheet or filament bases; compositions of bandages; or...

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424446, 424447, 424448, 424449, A61L 1500

Patent

active

053935292

ABSTRACT:
The present invention relates to active substance plasters for the controlled release of active substances to the skin consisting of a backing layer, an adhesive film connected therewith which film is water-soluble and consists of pressure-sensitive adhesive which comprises water-swellable polymers and in which the active substance is at least partially soluble, and of a removable protective layer covering the adhesive film, in which plasters the pressure-sensitive adhesive is based on homo and/or copolymers with at least one derivative of the acrylic or methacrylic acid, and which comprise as active substances, partially or completely dissolved in the adhesive, at a concentration of 0.5 to 10.0%-wt estrogens and their pharmaceutically acceptable derivatives alone or in combination with gestagens.

REFERENCES:
patent: 4039705 (1977-08-01), Douck et al.
patent: 4687481 (1987-08-01), Nuwayser
patent: 4810499 (1989-03-01), Nuwayser
patent: 4818540 (1989-04-01), Chien et al.
patent: 4906169 (1990-03-01), Chien et al.
patent: 4913905 (1990-04-01), Fankhaeuser et al.
"National Adhesives" technical bulletin, DUROTAK.

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