Estradiol derivatives and pharmaceutical compositions using...

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Cyclopentanohydrophenanthrene ring system doai

Reexamination Certificate

Rate now

  [ 0.00 ] – not rated yet Voters 0   Comments 0

Details

C514S177000, C514S178000, C514S182000, C552S521000, C552S530000, C552S531000, C552S532000, C552S610000, C552S611000, C552S625000, C552S626000

Reexamination Certificate

active

10856340

ABSTRACT:
Compositions and methods for treating mammalian disease characterized by undesirable angiogenesis by administering compounds of the general formula:wherein the variables are defined in the specification.

REFERENCES:
patent: 2584271 (1952-02-01), Huffman
patent: 2846453 (1958-08-01), Hoehn
patent: 3166577 (1965-01-01), Ringold et al.
patent: 3410879 (1968-11-01), Smith et al.
patent: 3470218 (1969-09-01), Farah
patent: 3492321 (1970-01-01), Crabbe
patent: 3496272 (1970-02-01), Kruger
patent: 3562260 (1971-02-01), De Ruggieri et al.
patent: 3956348 (1976-05-01), Hilscher
patent: 4172132 (1979-10-01), Draper et al.
patent: 4212864 (1980-07-01), Tax
patent: 4307086 (1981-12-01), Tax
patent: 4444767 (1984-04-01), Torelli et al.
patent: 4522758 (1985-06-01), Ward et al.
patent: 4552758 (1985-11-01), Murphy et al.
patent: 4634705 (1987-01-01), DeBernardis et al.
patent: 4743597 (1988-05-01), Javitt et al.
patent: 4808402 (1989-02-01), Leibovich et al.
patent: 4994443 (1991-02-01), Folkman et al.
patent: 5001116 (1991-03-01), Folkman et al.
patent: 5135919 (1992-08-01), Folkman et al.
patent: 5504074 (1996-04-01), D'Amato et al.
patent: 5521168 (1996-05-01), Clark
patent: 5621124 (1997-04-01), Seilz et al.
patent: 5629327 (1997-05-01), D'Amato
patent: 5629340 (1997-05-01), Kuwano et al.
patent: 5639725 (1997-06-01), O'Reilly et al.
patent: 5643900 (1997-07-01), Fotsis et al.
patent: 5646136 (1997-07-01), Petrow
patent: 5661143 (1997-08-01), D'Amato et al.
patent: 5716981 (1998-02-01), Hunter et al.
patent: 5733876 (1998-03-01), O'Reilly et al.
patent: 5763432 (1998-06-01), Tanabe et al.
patent: 5776704 (1998-07-01), O'Reilly et al.
patent: 5792845 (1998-08-01), O'Reilly et al.
patent: 5837682 (1998-11-01), O'Reilly
patent: 5854205 (1998-12-01), O'Reilly et al.
patent: 5854221 (1998-12-01), Cao et al.
patent: 5861372 (1999-01-01), Folkman et al.
patent: 5885795 (1999-03-01), O'Reilly et al.
patent: 5892069 (1999-04-01), D'Amato et al.
patent: 5919459 (1999-07-01), Nacy et al.
patent: 5958892 (1999-09-01), Mukhopadhyay et al.
patent: 5962445 (1999-10-01), Stewart
patent: 6011023 (2000-01-01), Clark et al.
patent: 6011024 (2000-01-01), Reed
patent: 6046186 (2000-04-01), Tanabe et al.
patent: 6051726 (2000-04-01), Sachdeva et al.
patent: 6054598 (2000-04-01), Sachdeva et al.
patent: 6136992 (2000-10-01), Ram et al.
patent: 6200966 (2001-03-01), Stewart
patent: 6239123 (2001-05-01), Green et al.
patent: 6284789 (2001-09-01), LaLonde et al.
patent: 6346510 (2002-02-01), O'Reilly et al.
patent: 6358940 (2002-03-01), Conney
patent: 6399773 (2002-06-01), Liu et al.
patent: 6410029 (2002-06-01), Mukhopadhyay et al.
patent: 6413513 (2002-07-01), Holaday
patent: 6448419 (2002-09-01), Paaren et al.
patent: 6514971 (2003-02-01), Thomas et al.
patent: 6528676 (2003-03-01), D'Amato et al.
patent: 6593321 (2003-07-01), Rao et al.
patent: 6605622 (2003-08-01), Green et al.
patent: 6723858 (2004-04-01), D'Amato et al.
patent: 6730665 (2004-05-01), Maran et al.
patent: 6953785 (2005-10-01), Ino et al.
patent: 2002/0002294 (2002-01-01), D'Amato et al.
patent: 2002/0035098 (2002-03-01), Slaga et al.
patent: 2002/0068724 (2002-06-01), Slaga et al.
patent: 2002/0082433 (2002-06-01), Agoston et al.
patent: 2002/0119959 (2002-08-01), D'Amato et al.
patent: 2002/0147183 (2002-10-01), Agoston et al.
patent: 2002/0165212 (2002-11-01), D'Amato et al.
patent: 2003/0027803 (2003-02-01), Slaga et al.
patent: 2003/0036539 (2003-02-01), Slaga et al.
patent: 2003/0050294 (2003-03-01), Jackson et al.
patent: 2003/0073674 (2003-04-01), Slaga et al.
patent: 2003/0096799 (2003-05-01), Rao et al.
patent: 2003/0096800 (2003-05-01), D'Amato et al.
patent: 2003/0229061 (2003-12-01), Rao et al.
patent: 2003/0236408 (2003-12-01), D'Amato et al.
patent: 2004/0053906 (2004-03-01), Slaga et al.
patent: 2004/0072813 (2004-04-01), D'Amato et al.
patent: 2004/0082558 (2004-04-01), Tofovic et al.
patent: 2004/0097479 (2004-05-01), Agoston et al.
patent: 2004/0116397 (2004-06-01), Slaga et al.
patent: 2004/0186086 (2004-09-01), Bunschoten et al.
patent: 2004/0198671 (2004-10-01), Bunschoten et al.
patent: 2004/0209855 (2004-10-01), Tofovic et al.
patent: 2005/0070488 (2005-03-01), Bennik et al.
patent: 2005/0148565 (2005-07-01), Cooperwood
patent: 2005/0182038 (2005-08-01), Cooperwood
patent: 2005/0192258 (2005-09-01), Agoston et al.
patent: 2005/0203075 (2005-09-01), Agoston et al.
patent: 2006/0025393 (2006-02-01), Liao et al.
patent: 2006/0079576 (2006-04-01), D'Amato et al.
patent: 2006/0116360 (2006-06-01), Fogler et al.
patent: 2006/0135796 (2006-06-01), Agoston et al.
patent: 2006/0183727 (2006-08-01), D'Amato et al.
patent: 2007/0004689 (2007-01-01), Agoston et al.
patent: 2007/0010505 (2007-01-01), Agoston et al.
patent: 1907330 (1969-10-01), None
patent: 2 004 516 (1970-09-01), None
patent: 27 57 157 (1977-12-01), None
patent: 3625315 (1988-01-01), None
patent: 0166937 (1986-08-01), None
patent: 0657175 (1995-06-01), None
patent: 857080 (1960-12-01), None
patent: 857081 (1960-12-01), None
patent: 1570597 (1980-07-01), None
patent: 2252498 (1992-08-01), None
patent: 39-5480 (1939-04-01), None
patent: 41 000100 (1966-01-01), None
patent: 42-928 (1967-01-01), None
patent: 58-131978 (1983-08-01), None
patent: 62-135472 (1987-06-01), None
patent: 63090763 (1988-04-01), None
patent: 63-119500 (1988-05-01), None
patent: 04-046120 (1992-02-01), None
patent: 09316000 (1997-09-01), None
patent: 11-209322 (1999-08-01), None
patent: 1240038 (1996-10-01), None
patent: WO 87/02367 (1987-04-01), None
patent: WO 88/03151 (1988-05-01), None
patent: WO 88/08002 (1988-10-01), None
patent: WO 90/15816 (1990-12-01), None
patent: WO 93/03729 (1993-03-01), None
patent: WO 93/10805 (1993-06-01), None
patent: WO 93/19746 (1993-10-01), None
patent: WO 95/04535 (1995-02-01), None
patent: WO 98/32763 (1998-07-01), None
patent: WO 98/40398 (1998-09-01), None
patent: WO 99/01142 (1999-01-01), None
patent: WO 99/22728 (1999-05-01), None
patent: WO 99/33858 (1999-07-01), None
patent: WO 99/33858 (1999-07-01), None
patent: WO 99/33859 (1999-07-01), None
patent: WO 99/35150 (1999-07-01), None
patent: WO 99/45018 (1999-09-01), None
patent: WO 00/07576 (2000-02-01), None
patent: WO 00/10552 (2000-03-01), None
patent: WO 00/66095 (2000-11-01), None
patent: WO 00/68246 (2000-11-01), None
patent: WO 01/27132 (2001-04-01), None
patent: WO 01/85755 (2001-11-01), None
patent: WO 02/15910 (2002-02-01), None
patent: WO 2004/101595 (2004-11-01), None
Gian Tondury et al., Zur Wirkung Der Sexualhormone Auf Wachstum und Differenzierung (See English Summary p. 55),Cambridge Philosophical Society,pp. 28-58, Dec. 17, 1955.
Mollendorff, W. Von, Wachstumsstorungen durch Geschlechtshormone, nach Untersuchungen an Gewebekulturen, pp. 187-202, Jun. 12, 1941.
Staples et al., Structural Requirements for Steroid Inhibition of Sheep Lymphocyte Mitogenesis in vitro,Steroidsvol/Iss: 44 (5), pp. 419-433, Nov. 1984.
U.S. Appl. No. 09/641,327, filed Aug. 18, 2000.
U.S. Appl. No. 09/644,387, filed Aug. 23, 2000.
U.S. Appl. No. 10/635,846, filed Aug. 5, 2003.
U.S. Appl. No. 10/789,471, filed Feb. 27, 2004.
Lilopristone/(1-[4-(Dimethylamino)phenyl]-17-hydroxy-17-(3-hydroxy-1-propenyl) estra-4,9-diene-3-one; AK 98734,Dictionary of Drugs(1990),Dict. of Steroids(1991),Dict. of Org. Cmpds(6th Ed) (1996),Dict. of Pharm Agents(1997), 1990.
(Paragraphs 583-584),The Merck Index 11th Edition, p. 88, 1989.
Research Plus Catalog, pp. 50-58, 1993.
News Article: Hoffman-La Roche Signs $70 Million Deal with Millenium on Genomics Technology,Genetic Engineering News, Apr. 15, 1994.
News Article: Advanced Drug Delivery Systems Peak Interest of Pharmaceutical & Biotech Firms,Genetic Engineering News, Apr. 15, 1994.
News Article: Nasal Spray for Treating Bleeding Disorders,Genetic Engineering News, Apr. 15, 1994.
2-Methoxystradiol—An Orally Active Endogenous Inhibitor of Angiogenesis,EntreMed Website Article, pp. 1-10, Jul. 11, 2000.
Aboulwafa et al., Synthesis and evaluation for uterotrophic and antiimplantation activities of 2-substituted estradiol derivatives,Steriods, vol. 57, pp. 199-204, Apr. 1

LandOfFree

Say what you really think

Search LandOfFree.com for the USA inventors and patents. Rate them and share your experience with other people.

Rating

Estradiol derivatives and pharmaceutical compositions using... does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Estradiol derivatives and pharmaceutical compositions using..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Estradiol derivatives and pharmaceutical compositions using... will most certainly appreciate the feedback.

Rate now

     

Profile ID: LFUS-PAI-O-3926615

  Search
All data on this website is collected from public sources. Our data reflects the most accurate information available at the time of publication.