Estimation method, human estrogen receptor alpha gene,...

Details Estimation method, human estrogen receptor alpha gene,... Estimation method, human estrogen receptor alpha gene,...

2006-05-16

2009-10-13

Martinell, James (Department: 1634)

Organic compounds -- part of the class 532-570 series

Organic compounds

Carbohydrates or derivatives

C536S023100, C536S024310, C435S006120

Reexamination Certificate

active

07601828

ABSTRACT:
Evaluation methods for evaluating susceptibility to multifactorial diseases in sexual differentiation disorders, human estrogen receptor alpha (α) genes carrying single nucleotide polymorphisms (SNPs) associated with the multifactorial diseases, DNAs containing the nucleotides at the SNPs, and diagnostic markers containing the DNAs are provided. Susceptibility to the multifactorial diseases can be evaluated by examining at least one of SNPs 8 to 14, or SNPs 10 to 14, in a human estrogen receptor α gene, and more precisely evaluated by examining a diplotype encompassing SNPs 10 to 14.

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