Estimation and biological consequences of oxidative metabolism

Chemistry: analytical and immunological testing – Lipids – triglycerides – cholesterol – or lipoproteins

Reexamination Certificate

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C436S063000, C436S174000, C436S178000

Reexamination Certificate

active

08039263

ABSTRACT:
The present invention relates to monitoring of oxidative metabolism and is, particularly, directed to a method for estimation of the lipid peroxide load or the consequent inflammatory state of a subject by measuring the concentration of the subject's oxidized HDL (high density lipoprotein) lipids. In addition, the invention is also directed to methods for the elimination of lipid peroxidation products, and attenuation of the resulting oxidative stress and inflammatory state in the human body by increasing the lipid peroxide transporting capacity of HDL.

REFERENCES:
patent: 5874313 (1999-02-01), Ahotupa
patent: 6869568 (2005-03-01), Fogelman et al.
patent: 2004/0241744 (2004-12-01), Kohno et al.
patent: 09033525 (1997-02-01), None
patent: 2004-69672 (2004-03-01), None
patent: WO-2005/055810 (2005-06-01), None
patent: WO-2006/014628 (2006-02-01), None
Hurtado et al. Atherosclerosis, vol. 125, 1996, pp. 39-46.
Ahotupa et al. Clinical Biochemistry, vol. 31, No. 4, 1998, pp. 257-261.
Nakano et al., “Immunochemical detection of circulating oxidized high-density liprotein with antioxidized apolipoprotein A-I monoclonal antibody” Journal of Laboratory and Clinical Medicine, Jun. 2003, vol. 141, No. 6, pp. 378-384.
Nakano et al., Immunoreactive circulating oxidized HDL concentrations do not increase in patients undergoing carotid endarterectomy: A comparative study for oxidized HDL and oxidized LDL concentrations in plasma, Clinica Chimica Acta, 2007, vol. 381, pp. 179-181.
Bergt et al., “Oxidized plasma high-density lipoprotein is decreased in Alzheimer's disease”, Free Radical Biology & Medicine, vol. 41, (2006), pp. 1542-1547.
Nakano et al., “NAD(P)H oxidase p22phoxGene C242T polymorphism and lipoprotein oxidation”, Clinica Chimica Acta, vol. 335, pp. 101-107, 2003.
“Lipid peroxides”, Published at the Centre for Cancer Education, University of Newcastle upon Tyne, Dec. 12, 1998, Retrieved from the Internet: <URL:http://cancerweb.ncl.uk/cgi-omd?lipid+peroxides abstract.
Parhami et al., “High-density lipoprotein regulates calcification of vascular cells” Circulation Research, 2002, vol. 91, pp. 570-576.
Ng., “Treating low HDL- from bench to bedside”, Clinical Biochemistry, 2004, vol. 37, pp. 649-659.
Ashen et al., “Low HDL Cholesterol Levels”, ACC Current Journal Review, Dec. 2005, pp. 15-16.
Mackness et al., “HDL, its enzymes and its potential to influence lipid peroxidation”, Atherosclerosis, vol. 115, 1995, pp. 243-253.
Panzenbock et al., “Formation of methionine sulfoxide-containing specific forms of oxidized high-density lipoproteins”, Biochimica of Biophysica Acta, vol. 1703, pp. 171-181, 2005.
Schnell et al., “Effects of a high polyunsaturated fat diet and vitamin E supplementation on high-density liporotein oxidation in humans”, Atherosclerosis, vol. 159, (2001), pp. 459-466.
Kajanachumpol et al., “Levels of Plasma Lipid Peroxide Products and Antioxidant Status in Rheumatoid Arthritis”, Southeast Asian J Trop Med Public Health, vol. 31, No. 2, Jun. 2000, pp. 335-338.
Santra et al., “Lipid peroxidation and vitamin E status in gestational diabetes mellitus”, Journal Obstet. Gynaecol. Res., vol. 29, No. 5, Oct. 2003, pp. 300-304.

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