Esters of prostacyclin-type compounds

Details Esters of prostacyclin-type compounds Esters of prostacyclin-type compounds

1979-06-14

1980-11-25

Gerstl, Robert

Organic compounds -- part of the class 532-570 series

Organic compounds

Carboxylic acid esters

C07C17700

Patent

active

042360196

ABSTRACT:
Acyl-substituted phenyl esters of prostacyclin-type compounds, for example the 4-acetylphenyl ester of prostacyclin (PGI.sub.2) illustrated by the formula ##STR1## and including esters of the isomeric 6-hydroxy-PGI.sub.1 and 6-keto-PGF.sub.1.alpha. compounds, said esters having pharmacological activity. Processes for preparing them and the appropriate intermediates are disclosed.

REFERENCES:
Kojima et al., Tet. Letters, 3743 (1978).

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