Esters of prostacyclin-type compounds

Details Esters of prostacyclin-type compounds Esters of prostacyclin-type compounds

1979-06-14

1980-07-08

Killos, Paul J.

Organic compounds -- part of the class 532-570 series

Organic compounds

Carboxylic acid esters

560121, 562463, 562503, C07C17700

Patent

active

042118794

ABSTRACT:
Acyl-substituted phenyl esters of prostacyclin-type compounds, for example the 4-acetylphenyl ester of prostacyclin (PGI.sub.2) illustrated by the formula ##STR1## and including esters of the isomeric 6-hydroxy-PGF.sub.1 and 6-keto-PGF.sub.1.alpha. compounds, said esters having pharmacological acitivity. Processes for preparing them and the appropriate intermediates are disclosed.

REFERENCES:
Derwent Abstracts, 29303A/16, J53023, 06-03-75.
Derwent Abstracts, 29302A/16, J53023-953, 06-03-78.
Chem. Abst. 87:200908k, Takaka, 02-03-77.

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