Esters of penicillanic acid sulfone

Details Esters of penicillanic acid sulfone Esters of penicillanic acid sulfone

1980-12-11

1982-11-30

Rizzo, Nicholas S.

Chemistry of carbon compounds

Miscellaneous organic carbon compounds

C-metal

424270, 424271, C07D49900, A61K 31425

Patent

active

043615139

ABSTRACT:
A process for preparing halomethyl esters of penicillanic acid sulfone, intermediates to beta-lactamase inhibitors, from the corresponding substituted thiomethyl and sulfinylmethyl esters and a halogenating agent. The thiomethyl and sulfinylmethyl esters of penicillanic acid sulfone are useful intermediates.

REFERENCES:
patent: 4241050 (1980-12-01), Barth
patent: 4256733 (1981-03-01), Barth
patent: 4272439 (1981-06-01), Ganguly et al.
patent: 4331677 (1982-05-01), Foglio et al.
Chem. Pharm. Bull., 27 (5), 1199 (1979).
J. Org. Chem., 44, 1178 (1979).

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