Esters of mercapto acyl-carnitines and pharmaceutical compositio

Details Esters of mercapto acyl-carnitines and pharmaceutical compositio Esters of mercapto acyl-carnitines and pharmaceutical compositio

1982-03-15

1986-01-28

Garner, Vivian

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Ester doai

2604025, 260390, 424DIG13, 560147, 560125, 560 16, 560 15, 514529, 556134, A61K 3122, A61K 3123, C07C149243

Patent

active

045672008

ABSTRACT:
A novel class of esters of mercapto acyl-carnitines is disclosed, wherein the mercapto acyl radical is the radical of saturated mercapto acids having from 2 to 10 carbon atoms. These esters of mercapto acyl-carnitines are prepared e.g. by first preparing the corresponding ester of halogen acyl-carnitine and then substituting therein, by nucleophylic substitution, the --SH group for the halogen atom.
These esters of mercapto acyl-carnitines are useful therapeutic agents, e.g. for the treatment of intoxications and burns, and as mucolytic agents.

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