Esters of dihydroapovincaminic acid

Details Esters of dihydroapovincaminic acid Esters of dihydroapovincaminic acid

1975-01-31

1976-10-19

Trousof, Natalie

Chemistry of carbon compounds

Miscellaneous organic carbon compounds

C-metal

424267, C07D40114

Patent

active

039870499

ABSTRACT:
The invention relates to esters of general formula (I) ##SPC1##
in which R represents a straight or branched saturated or unsaturated aliphatic hydrocarbon group containing 2 to 6 carbon atoms optionally bearing 1 or 2 substituents which substituents may be the same or different and each represents a hydroxyl group or an alkoxy group whose alkyl portion is linear or branched and contains 1 to 6 carbon atoms, and their pharmaceutically acceptable acid addition salts, to processes for their preparation and to pharmaceutical compositions containing them. The esters and salts are suitable for the treatment of vascular and cerebral disorders.

REFERENCES:
patent: 3770724 (1973-11-01), Warnant et al.
patent: 3884927 (1975-05-01), Martel et al.
Blaha et al. Collection Czechoslov. Chem. Commun. 1968, vol. 33, pp. 3833-3847.
Omnium Chimique Chem. Abst. 1973, vol. 78, No. 30049a.

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