Drug – bio-affecting and body treating compositions – Radionuclide or intended radionuclide containing; adjuvant... – Molecular bilayer structure
Patent
1984-09-07
1986-01-28
Trousof, Natalie
Drug, bio-affecting and body treating compositions
Radionuclide or intended radionuclide containing; adjuvant...
Molecular bilayer structure
560 47, A61K 4904, C07C10168
Patent
active
045670340
ABSTRACT:
New X-ray contrast agents are provided which are esters of diatrizoic acid having the structure ##STR1## wherein R is an alkyl group of 10 to 22 carbons or a group of the structure ##STR2## wherein R.sup.1 is an alkyl group of 2 to 15 carbons. X-ray contrast medium containing the above X-ray contrast agent and a carrier therefor such as a liposome carrier, and a method for the X-ray visualization of body cavities and organs are also provided.
REFERENCES:
patent: 3097228 (1963-07-01), Larsen
patent: 3128301 (1964-04-01), Larsen et al.
patent: 3476802 (1969-11-01), Holtermann et al.
patent: 3637824 (1972-01-01), Holtermann et al.
patent: 3772376 (1973-11-01), Ekstrand et al.
patent: 3795698 (1974-03-01), Soulal et al.
patent: 4018783 (1977-04-01), Soulal et al.
patent: 4132731 (1979-01-01), Klieger et al.
patent: 4192859 (1980-03-01), Mackaness et al.
patent: 4225725 (1980-09-01), Hoey
patent: 4285928 (1981-08-01), Wada et al.
Havron et al., "Radiopaque Liposomes: A Promising New Contrast Material for Computed Tomography of the Spleen", Radiology, 140:507-511, Aug. 1981.
Ryan et al., "The Preparation and Characterization of Liposomes Containing X-Ray Contrast Agents", Biochemica et Biophysica Acta. 756 (1983), 106-110 (Elsevier Biomedical Press).
Charles Isabel
Robinson Malcolm
E. R. Squibb & Sons Inc.
Gray Bruce D.
Levinson Lawrence S.
Rodney Burton
Trousof Natalie
LandOfFree
Esters of diatrizoic acid as X-ray contrast agents does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Esters of diatrizoic acid as X-ray contrast agents, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Esters of diatrizoic acid as X-ray contrast agents will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-1305611