Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Silicon containing doai
Patent
1984-10-25
1987-03-03
Shaver, Paul F.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Silicon containing doai
556402, 560 20, 560130, 560156, 2603972, A61K 31695, A61L 2300, A01N 5500, C07F 502
Patent
active
046475559
ABSTRACT:
Ester analogues of boron analogues of amino acid are disclosed. Also disced is a method of forming the ester analogues in high yield by condensation of the corresponding acids and alcohols with dicylohexylcarbodiimide at room temperature in dichloromethane. The disclosed compounds have shown interesting biological activities, in particular, hypolipidemic activity as well as significant antitumor and antiarthritic activities.
REFERENCES:
patent: 3018299 (1962-01-01), Pike
patent: 3265737 (1966-08-01), Miller
patent: 4035409 (1977-07-01), Cummings
patent: 4440941 (1984-04-01), Suh et al.
Hall Iris H.
McPhail Andrew T.
Spielvogel Bernard F.
Shaver Paul F.
Soderling Gail S.
Taucher Peter A.
The United States of America as represented by the Secretary of
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