Esters of acyl-carnitines, process for preparing same and pharma

Details Esters of acyl-carnitines, process for preparing same and pharma Esters of acyl-carnitines, process for preparing same and pharma

1982-05-26

1984-03-27

Reamer, James H.

Drug, bio-affecting and body treating compositions

Antigen, epitope, or other immunospecific immunoeffector

Bacterium or component thereof or substance produced by said...

424311, 424312, 546300, 560170, A61K 3144, C07C21172

Patent

active

044394381

ABSTRACT:
Novel esters of acyl-carnitines having general formula ##STR1## wherein R' is acetyl, propionyl, butyryl (unsubstituted or halogen-substituted), isobutyryl, .beta.-hydroxy butyryl, acetoacetyl, pantothenyl and linoleyl, and R" is an alkoxy radical either unsubstituted alkoxy, typically: isobutyloxy or substituted alkoxy, typically: trichloroethyloxy) are therapeutically effective in the treatment of myocardial hypocontractility and as antidepresants.

REFERENCES:
patent: 4032641 (1977-06-01), Chibata et al.
Riuniti, Chem. Abst., vol. 92, #215769(t) (1980).
Mino et al, Chem. Abst., vol. 71, #151495(f) (1972).
Strack et al, Chem. Abst., vol. 64, #19398(f) (1966).

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