Esters of 7-[2-(2-aminothiazol-4-yl)-2-(syn)-methoxyiminoacetami

Organic compounds -- part of the class 532-570 series – Organic compounds – Heterocyclic carbon compounds containing a hetero ring...

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540222, 540227, C07D50122

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active

046803904

ABSTRACT:
The compounds are of the class of esters of 7-[2-(2-aminothiazol-4-yl-)-2-(syn)methoxyiminoacetamido] cephalosporin derivatives, including lower alkoxymethyl, .alpha.-lower alkoxy-.alpha.-substituted methyl, lower alkylthiomethyl, acyloxymethyl, ethoxycarbonyloxy-1-methylmethyl and .alpha.- acyloxy-.alpha.-substituted methyl esters. The compounds are useful against a broad spectrum of bacteria, particularly gram-negative bacteria, and may be administered in the form of injections, capsules, tablets and granules.

REFERENCES:
patent: 3935204 (1976-01-01), Dahlen
patent: 4041161 (1977-08-01), Kocsis
patent: 4092476 (1978-05-01), Bentley
patent: 4098888 (1978-07-01), Ochiai
patent: 4202893 (1980-05-01), Heymes
Nakao Chemical Abstracts 92: 146752t (4/12/78).

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