Esterified hydroxy dihydropyridinones for treating diseases asso

Details Esterified hydroxy dihydropyridinones for treating diseases asso Esterified hydroxy dihydropyridinones for treating diseases asso

1988-11-01

1990-03-13

Schwartz, Richard A.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

514343, 514346, 514348, 546193, 546194, 546281, 546292, 546296, C07D40112, A61K 31445

Patent

active

049083716

ABSTRACT:
3-Substituted 4(1H)-pyridone compounds of formula ##STR1## wherein R.sub.1 is an unsubstituted or substituted hydrocarbon radical, X is a bond or a group of formula --O-- or --N(R.sub.3)--, wherein R.sub.3 is hydrogen or an unsubstituted or substituted hydrocarbon radical, and R.sub.2 is an unsubstituted or substituted hydrocarbon radical, or wherein R.sub.2 and R.sub.3, when taken together, are an unsubstituted or substituted divalent hydrocarbon radical, and wherein the other ring carbon atoms of the 4(1H)-pyridinone ring, independently of one another, are unsubstituted or substituted by an unsubstituted or substituted hydrocarbon radical or by etherified or esterified hydroxy, and salts of compounds of formula I with salt-forming properties, form chelate-type metal complexes, especially with trivalent metal ions, and can be used, for example, as pharmacologically active compounds.

REFERENCES:
patent: 4550101 (1985-10-01), Hider et al.
patent: 4585780 (1986-04-01), Hider et al.
patent: 4587240 (1986-05-01), Hider et al.
patent: 4665064 (1987-05-01), Hider et al.
patent: 4666927 (1987-05-01), Hider et al.

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