Esterified-2(3-lower-alkyl-amino-propoxy)-3-cyano-pyridines and

Details Esterified-2(3-lower-alkyl-amino-propoxy)-3-cyano-pyridines and Esterified-2(3-lower-alkyl-amino-propoxy)-3-cyano-pyridines and

1976-06-15

1977-10-11

Rotman, Alan L.

Drug, bio-affecting and body treating compositions

Antigen, epitope, or other immunospecific immunoeffector

Bacterium or component thereof or substance produced by said...

2602949, 260295R, C07D21357, A61K 31395

Patent

active

040536050

ABSTRACT:
Novel cyano substituted (3-loweralkylamino-2-acyl-O-propoxy)pyridines, their pharmaceutically acceptable salts and their preparation are disclosed. The pyridines are vasodilators having antihypertensive activity of rapid onset and extended duration and reduced tendency to cause undesirable tachychardia; they are also .beta.-adrenergic blocking agents.

REFERENCES:
patent: 3946009 (1976-03-01), Wasson et al.
patent: 4000282 (1976-12-01), Baldwin
Burger Medicinal Chemistry, Third Edition, Part II, Wiley-Interscience Pub. pp. 1253-1278, (1970).

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