Esterification process using methoxymethyl-P-toluenesulfonate

Chemistry of carbon compounds – Miscellaneous organic carbon compounds – C-metal

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260456P, 544 16, 544 19, 544 24, 544 25, 544 27, C07D49908, C07D50102

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active

042474612

ABSTRACT:
A new esterifying agent, i.e. methoxymethyl tosylate, is provided for use in preparing methoxymethyl esters of organic carboxylic acids. The new esterifying agent is found to be particularly advantageous in the esterification of penicillin 3-carboxyl groups or cephalosporin 4-carboxyl groups to the methoxymethyl ester group.

REFERENCES:
patent: 3697507 (1972-10-01), Frederiksen et al.
patent: 3819643 (1974-06-01), Frederiksen et al.
patent: 3873521 (1975-03-01), Eckstrom et al.
patent: 4185015 (1980-01-01), Sleezer et al.

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