Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Patent
1988-09-23
1990-06-26
Lee, Mary C.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
514533, 514534, 548253, 548337, 549549, 549 78, 549502, 549497, 560 15, 560 16, C07C14940, A61K 3110
Patent
active
049372530
ABSTRACT:
This invention relates to ester prodrugs for alkanoic acid compounds useful as leukotriene antagonists, and pharmaceutical compositions containing such ester prodrug compounds. This invention also relates to methods of treating diseases in which leukotrienes are a factor by administration of an effective amount of the above compounds or compositions.
REFERENCES:
patent: 4069744 (1986-09-01), Young et al.
Gleason et al., J. Med. Chem. vol. 3, No. 6 (1987), pp. 959-961.
Derwent Patent Abstract 84-014267/03 of Japanese Patent Appln. 58206556A, published Dec. 1, 1983.
Derwent Patent Abstract 85-026589/05 of European Patent Appln. 132366A, published Jan. 30, 1985.
Chem. Abstract 96(17):143290n (1983).
Chem. Abstract 94(9): 64755y (1981).
Chemical Abstracts, vol. 96, 98909h (1982).
Chemical Abstracts, vol. 101, 151857g (1984).
Gleason John G.
Hall Ralph F.
Newton John F.
Phipps Kathleen A.
Smallheer Joanne
Howard M. S.
Kanagy James M.
Lee Mary C.
Lentz Edward T.
SmithKline Beecham Corporation
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