Ester of ascorbic acid 2-phosphate and pharmaceutical use

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Phosphorus containing other than solely as part of an...

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514 99, 514100, 540 5, 546 23, 549220, 549222, A61K 31665, C07F 909

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active

049391283

ABSTRACT:
The present invention relates to a compound of the formula: ##STR1## wherein R.sup.1 is a hydrogen atom, carboxylic acid acyl or carbamoyl which may be substituted; R is an aliphatic hydrocarbon group which may be substituted or alicylic hydrocarbon group which may be substituted, or a salt thereof.
The compound of the present invention has the effects to prevent and improve dysfunctions caused by oxygen free radicals, and can be used as preventive and therapeutic drugs against dysfunctions in the circulatory system.

REFERENCES:
patent: 4564686 (1986-01-01), Ogata
Hiroaki Nomura et al., "Studies on L-Ascorbic Acid Derivatives The Ferric Chloride Reaction of L-Ascorbic Acid 3-Phosphate and its Application for the Colorimetric Determination", Chem. Pharm. Bull., vol. 19(2), (1971) pp. 335-340.

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