Ester derivatives

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...

Reexamination Certificate

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Details

C546S124000, C546S125000, C546S127000

Reexamination Certificate

active

10983613

ABSTRACT:
This invention relates to compounds which exhibit selective muscarinic M3receptor antagonism, have little side effects, are suitable for inhalation therapy and are useful as treating agents of respiratory system diseases, of the general formula (I);[in which A signifies a group expressed by a formula (a0) or (b0);Ar signifies optionally substituted aryl or heteroaryl; B1and B2signify aliphatic hydrocarbon; R1signifies fluorine-substituted cycloalkyl; R2, R3and R4signify lower alkyl, single bond or alkylene bonded to B1, or R2and R3are united to signify alkylene; R5and R7signify hydrogen, lower alkyl, or a single bond or alkylene bonded to B2; R6signifies hydrogen, lower alkyl or a group expressed as —N(R8)R9; and X−signifies an anion].

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