Establishment, characterization and differentiation of a new meg

Details Establishment, characterization and differentiation of a new meg Establishment, characterization and differentiation of a new meg

1988-08-17

1992-07-07

Weimar, Elizabeth C.

Chemistry: molecular biology and microbiology

Measuring or testing process involving enzymes or...

Involving viable micro-organism

435 701, 435 703, 435 704, 4352401, 4352402, 43524025, C12Q 102, C12P 2100, C12N 500, C12N 502

Patent

active

051282453

ABSTRACT:
A stable mutant human megakaryocytic cell line is disclosed which is useful for the study of megakaryocytopoiesis, platelet formation and production, platelet component formation, and the identification and characterization of factors which modulate megakaryocytopoiesis.

REFERENCES:
patent: 4710381 (1987-12-01), Kunicki et al.
S. M. Greenberg et al., Blood 70 (Supp 1): 154a, Abstract No. 470 (1987)
S. M. Greenberg-Sepersky et al., Thromb. Res. 24:299-306 (1981).
M. Ogura et al., Blood 66:1384-1392 (1985).
D. Seigneurin et al., Exp. Hematol. 15:822-832 (1987).
P. Martin et al., Science 216:1233-1235 (1982).
A. Tabilio et al., EMBO J 3:453-459 (1984).
R. Michalevicz et al., Leuk. Res. 9:441-448 (1985).
G. W. Sledge et al., Cancer Res. 46:2155-2159 (1986).
J. Loscalzo et al., Biochem. 23:3880-3886 (1984).
D. D. Wagner et al., J. Cell Biol. 99:2123-2130 (1984).
S. M. Greenberg et al., J. Biol. Chem. 262:3269-3277 (1987).
Greenberg et al. (ARI), "Development and Characterization of a new megakaryocytic cell line: The Dami Cell", Blood 70(5) 1987.
Greenberg et al., "Characterization of a New Megakaryocytic Cell Line: The Dami Cell", Blood, vol. 72(6), 1968-1977, Dec.-88.
Morgan et al. (AT3), "Novel peripheral blood derived human cell lines with properties of megakaryocytes", J. Cell Biology, vol. 100, 565-573, 1985.
Kieffer et al., "Expression of Platelet Glycoprotein Ib.alpha. in HEL cells", J. Biological Chemistry, vol. 261, 15854-15862, 1986.
Kellar et al., "Thrombopoietin stimulation of megakaryocytopoiesis in Agar Culture", Megakaryocyte Development and Function, pp. 209-213, 1986.

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