Escape mutants of newcastle disease virus as marker vaccines

Details Escape mutants of newcastle disease virus as marker vaccines Escape mutants of newcastle disease virus as marker vaccines

2006-05-09

2006-05-09

Housel, James (Department: 1648)

Drug, bio-affecting and body treating compositions

Antigen, epitope, or other immunospecific immunoeffector

Virus or component thereof

C530S350000

Reexamination Certificate

active

07041299

ABSTRACT:
A vaccine against Newcastle Disease contains one or more mutant immunogens of the NDW strain. The mutant immunogen lacks the antigenic binding site on the F glycoprotein which is recognized by the monoclonal antibody mAb 54. Reagent kits and assay methods help to distinguish vaccinated members of a poultry flock from those that may have been infected with wild-type Newcastle Disease virus.

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