Erythropoietin with high specific activity

Chemistry: natural resins or derivatives; peptides or proteins; – Proteins – i.e. – more than 100 amino acid residues – Blood proteins or globulins – e.g. – proteoglycans – platelet...

Reexamination Certificate

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Details

C530S350000, C530S395000, C514S002600, C424S001690

Reexamination Certificate

active

07659373

ABSTRACT:
The invention concerns new EPO compositions with high specific activity which are characterized by a high proportion of N-acetyl-lactosamine units or/and tetraantennary branches in the carbohydrate structure. In addition the invention concerns a process for producing such EPO products.

REFERENCES:
patent: 4745099 (1988-05-01), Akamatsu et al.
patent: 4835260 (1989-05-01), Shoemaker
patent: 5106954 (1992-04-01), Fibi et al.
patent: 5459031 (1995-10-01), Blumen et al.
patent: 5641670 (1997-06-01), Treco et al.
patent: 5789390 (1998-08-01), Descamps et al.
patent: 5856298 (1999-01-01), Strickland
patent: WO-93/09222 (1993-05-01), None
patent: WO-94/12650 (1994-06-01), None
patent: WO-95/31560 (1995-11-01), None
patent: WO-96/35718 (1996-11-01), None
patent: WO-99/05268 (1999-02-01), None
Watson et al. Structure determination of the intact major sialylated oligosaccharide chains of recombinant human erythropoietin expressed in Chinese hamster ovary cells. Glycobiology. 1994, 4(2): 227-237.
Takeuchi et al. Relationship between sugar chain structure and biological activity of recombinant human erythropoietin produced in Chinese hamster ovary cell. Proc. Natl. Acad. Sci. Oct. 1989, 86: 7810-7822.
Takeuchi et al. #2. Structures and functional roles of the sugar chains of human erythropoietins. Glycobiology. Sep. 1991;1(4):337-46. Review.
Descamps et al. Keratinocytes as a target for gene therapy. Sustained production of erythropoietin in mice by human keratinocytes transduced with an adenoassociated virus vector. Arch Dermatol. Oct. 1996;132(10):1207-11 (abstract).
Ohashi, et al., “Purification and Characterization of Recombinant Human Erythropoietin Expressed in Human Cervix Carcinoma HeLa Cells,” Trends in Animal Cell Culture Technology (1990) 115-120.
Bioindustry, vol. 8, No. 4 (1991), p. 21-31.
Summary Japan Fermentation Technology Associated 1991 Meeting, 1991, p. 30.

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