Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Peptide containing doai
Reexamination Certificate
2011-03-15
2011-03-15
Russel, Jeffrey E (Department: 1654)
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Peptide containing doai
C514S021400
Reexamination Certificate
active
07906485
ABSTRACT:
The present invention relates to peptide compounds that are agonists of the erythropoietin receptor (EPO-R). The invention also relates to therapeutic methods using such peptide compounds to treat disorders associated with insufficient or defective red blood cell production, including pure red cell aplasia (PRCA). Pharmaceutical compositions, which comprise the peptide compounds of the invention, and dosages are also provided.
REFERENCES:
patent: 4179337 (1979-12-01), Davis et al.
patent: 4677195 (1987-06-01), Hewick et al.
patent: 4703008 (1987-10-01), Lin
patent: 4925673 (1990-05-01), Steiner et al.
patent: 5006333 (1991-04-01), Saifer et al.
patent: 5013556 (1991-05-01), Woodle et al.
patent: 5143854 (1992-09-01), Pirrung et al.
patent: 5278065 (1994-01-01), D'Andrea et al.
patent: 5283317 (1994-02-01), Saifer et al.
patent: 5284656 (1994-02-01), Platz et al.
patent: 5292654 (1994-03-01), Yoshimura et al.
patent: 5378808 (1995-01-01), D'Andrea et al.
patent: 5424186 (1995-06-01), Fodor et al.
patent: 5432018 (1995-07-01), Dower et al.
patent: 5441868 (1995-08-01), Lin
patent: 5451569 (1995-09-01), Wong et al.
patent: 5468478 (1995-11-01), Saifer et al.
patent: 5547933 (1996-08-01), Lin
patent: 5580853 (1996-12-01), Sytkowski
patent: 5614184 (1997-03-01), Sytkowski et al.
patent: 5618698 (1997-04-01), Lin
patent: 5621080 (1997-04-01), Lin
patent: 5654276 (1997-08-01), Barrett et al.
patent: 5668110 (1997-09-01), Barrett et al.
patent: 5672662 (1997-09-01), Harris et al.
patent: 5677280 (1997-10-01), Barrett et al.
patent: 5683983 (1997-11-01), Barrett et al.
patent: 5747446 (1998-05-01), Sytkowski
patent: 5756349 (1998-05-01), Lin
patent: 5767078 (1998-06-01), Johnson et al.
patent: 5770358 (1998-06-01), Dower et al.
patent: 5773569 (1998-06-01), Wrighton et al.
patent: 5830851 (1998-11-01), Wrighton et al.
patent: 5869451 (1999-02-01), Dower et al.
patent: 5919758 (1999-07-01), Sytkowski
patent: 5932546 (1999-08-01), Barrett et al.
patent: 5955422 (1999-09-01), Lin
patent: 5986047 (1999-11-01), Wrighton et al.
patent: 6048971 (2000-04-01), Sytkowski et al.
patent: 6077939 (2000-06-01), Wei et al.
patent: 6083913 (2000-07-01), Dower et al.
patent: 6103879 (2000-08-01), Chaovapong et al.
patent: 6107272 (2000-08-01), Sytkowski
patent: 6113906 (2000-09-01), Greenwald et al.
patent: 6121238 (2000-09-01), Dower et al.
patent: 6153407 (2000-11-01), Sytkowski et al.
patent: 6221608 (2001-04-01), Middleton et al.
patent: 6251864 (2001-06-01), Dower et al.
patent: 6270170 (2001-08-01), Isogai et al.
patent: 6333031 (2001-12-01), Olsson et al.
patent: 6340742 (2002-01-01), Burg et al.
patent: 6465430 (2002-10-01), Dower et al.
patent: 6489293 (2002-12-01), Sytkowski et al.
patent: 6498155 (2002-12-01), Luengo et al.
patent: 6506362 (2003-01-01), Dower et al.
patent: 6531121 (2003-03-01), Brines et al.
patent: 6552008 (2003-04-01), Duffy et al.
patent: 6552167 (2003-04-01), Rose
patent: 6576235 (2003-06-01), Williams et al.
patent: 6583272 (2003-06-01), Bailon
patent: 6660843 (2003-12-01), Feige et al.
patent: 6703480 (2004-03-01), Balu
patent: 6777387 (2004-08-01), Greenwald et al.
patent: 6783965 (2004-08-01), Sherman et al.
patent: 6784154 (2004-08-01), Westenfelder
patent: 6858630 (2005-02-01), Luengo et al.
patent: 7084245 (2006-08-01), Holmes et al.
patent: 7396913 (2008-07-01), DeVries et al.
patent: 7550433 (2009-06-01), Duliege et al.
patent: 2002/0015691 (2002-02-01), Greenwald et al.
patent: 2002/0037841 (2002-03-01), Papadimitriou et al.
patent: 2002/0052317 (2002-05-01), Itri et al.
patent: 2002/0086816 (2002-07-01), Brines et al.
patent: 2002/0115833 (2002-08-01), Burg et al.
patent: 2002/0160013 (2002-10-01), Olsson et al.
patent: 2002/0169128 (2002-11-01), Sigounas et al.
patent: 2002/0177166 (2002-11-01), Guthridge et al.
patent: 2003/0009018 (2003-01-01), Maeda et al.
patent: 2003/0012777 (2003-01-01), Sherman et al.
patent: 2003/0050269 (2003-03-01), Escary
patent: 2003/0083251 (2003-05-01), Westenfelder
patent: 2003/0083361 (2003-05-01), Luengo et al.
patent: 2003/0104988 (2003-06-01), Brines et al.
patent: 2003/0120045 (2003-06-01), Bailon
patent: 2003/0125262 (2003-07-01), Kiessling et al.
patent: 2003/0134798 (2003-07-01), Brines et al.
patent: 2003/0166249 (2003-09-01), Williams et al.
patent: 2003/0191291 (2003-10-01), Kochendoerfer et al.
patent: 2004/0062746 (2004-04-01), Martinez et al.
patent: 2004/0092499 (2004-05-01), Erbey et al.
patent: 2004/0126361 (2004-07-01), Saifer et al.
patent: 2004/0136952 (2004-07-01), Bhaskaran et al.
patent: 2005/0014240 (2005-01-01), Sherman et al.
patent: 2005/0137329 (2005-06-01), Holmes et al.
patent: 2005/0176627 (2005-08-01), Cerami et al.
patent: 2006/0040858 (2006-02-01), Holmes et al.
patent: 2007/0027074 (2007-02-01), Holmes et al.
patent: 0 400 472 (1990-12-01), None
patent: WO-90/08822 (1990-08-01), None
patent: WO-90/12874 (1990-11-01), None
patent: WO-90/15070 (1990-12-01), None
patent: WO-92/16221 (1992-10-01), None
patent: WO-92/16555 (1992-10-01), None
patent: WO-96/40189 (1996-12-01), None
patent: WO-96/40749 (1996-12-01), None
patent: WO-96/40750 (1996-12-01), None
patent: WO-96/40772 (1996-12-01), None
patent: WO-98/25965 (1998-06-01), None
patent: WO-00/07629 (2000-02-01), None
patent: WO-00/12587 (2000-03-01), None
patent: WO-00/24770 (2000-05-01), None
patent: WO-00/24782 (2000-05-01), None
patent: WO-00/33881 (2000-06-01), None
patent: WO-01/38342 (2001-05-01), None
patent: WO-01/59078 (2001-08-01), None
patent: WO-01/91780 (2001-12-01), None
patent: WO-02/065988 (2002-08-01), None
patent: WO-03/002716 (2003-01-01), None
patent: WO-2004/014424 (2004-02-01), None
patent: WO-2004/030617 (2004-04-01), None
patent: WO-2004/060299 (2004-07-01), None
patent: WO-2004/060300 (2004-07-01), None
patent: WO-2004/100997 (2004-11-01), None
patent: WO-2004/101600 (2004-11-01), None
patent: WO-2004/101606 (2004-11-01), None
patent: WO-2004/101611 (2004-11-01), None
patent: WO-2004101606 (2004-11-01), None
patent: WO-2004101611 (2004-11-01), None
patent: WO-2004/108070 (2004-12-01), None
Verhelst et al. Treatment of erythropoietin-induced pure red cell aplasia . . . The Lancet. May 29, 2004, vol. 363, No. 9423, pp. 1768-1771.
Abuchowski, A.,et al., “Effect of covalent attachment of polyethylene glycol on immunogenicity and circulating life of bovine liver catalase,” J. Biol. Chem, vol. 252, pp. 3582-3586 (1977).
Beauchamp, C.O., et al., “A new procedure for the synthesis of polytheylene glycol-protein adducts; effects on function, receptor recognition, and clearance of superoxide dismutase, lactoferrin, and alpha 2-macroglobulin”, Anal Biochem., vol. 131, pp. 25-33 (1983).
Chen, R.H., et al., “Properties of two urate oxidases modified by the covalent attachment of poly(ethylene glycol)”, Biochem. Biophys. Acta., vol. 660, pp. 293-298 (1981).
Francis, G.E., et al., “PEGylation of cytokines and other therapeutic proteins and peptides: The importance of biological optimisation of coupling techniques”, Int. J. Hematol, vol. 68, pp. 1-18 (1998).
Greenwald, R.B., et al. (2003) Controlled release of proteins from their poly(ethylene glycol) conjugates: drug delivery systems employing 1,6-elimination. Bioconjug. Chem. 14:395-403.
Greenwald, R.B., et al. (2003) Effective drug delivery by PEGylated drug conjugates. Adv. Drug Deliv. Rev. 55:217-250.
Johnson et al., “Identification of a 13 amino acid peptide mimetic of erythropoietin and description of amino acids critical for the mimetic activity of EMP1”, Biochemistry 37: 3699-3710 (1998).
Johnson, D.L., et al., “Amino-terminal dimerization of an erythropoietin mimetic peptide results in increased erythropoietic activity”, Chem. Biol., vol. 4, pp. 939-950 (1997).
Kita, Y., et al., “Characterization of a polyethylene glycol conjugate of recombinant human interferon-gamma”, Dr. Des. Deliv. vol. 6, pp. 157-167 (1990).
Knauf, M.J., et al., “Relationship of effective molecular size to systemic clearance in rats of recombinant interleukin-2 chemically modified with water-soluble
Duliege Anne-Marie
Leuther Kerstin
Naso Robert Barnett
Stead Richard
Woodburn Kathryn Wynne
Affymax, Inc.
Fish & Richardson P.C.
Russel Jeffrey E
LandOfFree
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