Erythromycin salt with mucosecretolytic and fluidizing activity

Details Erythromycin salt with mucosecretolytic and fluidizing activity Erythromycin salt with mucosecretolytic and fluidizing activity

1985-03-14

1987-06-09

Brown, Johnnie R.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Carbohydrate doai

536 72, A61K 3171, C07H 1708

Patent

active

046720553

ABSTRACT:
The erythromycin salt of 5-(3-carboxy-1-oxopropoxy)-.alpha.,.alpha., 4-trimethyl-3-cyclohesene-1-methanol acid is described.
This salt shows a mucosecretolytic and fluidizing activity. There is further described a process for the preparation of said salt, as well as pharmaceutical compositions with mucosecretolytic and fluidizing action which contain the novel salt.

REFERENCES:
patent: 2870138 (1959-01-01), Murray et al.
patent: 4219641 (1980-08-01), Desposato et al.
patent: 4264765 (1981-04-01), Bodor et al.
Chemical Abstracts, vol. 90, No. 10, 5th Mar. 1979, p. 8, No. 80589v, "Fluorimetric Determination of Erythromycin and Erythromycin Ethylsuccinate in Serum by a High-Performance Liquid Chromatographic Post-Column . . . ".

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