Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Carbohydrate doai
Patent
1985-11-12
1987-08-11
Brown, Johnnie R.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Carbohydrate doai
536 72, A61K 3171, C07H 1708
Patent
active
046862072
ABSTRACT:
Disclosed herein are erythromycin derivatives of the formula ##STR1## wherein R.sub.1 is lower alkyl, aryl, alkene, aryl halide, alkylamino, hydroxyalkyl and furanyl, and pharmaceutically acceptable salts thereof. These compounds have improved oral absorption, reduced effects on gastrointestinal motility, increased acid stability and longer serum half-lives.
REFERENCES:
patent: 3842068 (1974-10-01), Tadanier et al.
patent: 4476298 (1984-10-01), Morimoto et al.
Bacino David J.
Freiberg Leslie A.
Abbott Laboratories
Brown Johnnie R.
Katz Martin L.
Roth Michael J.
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