Erythrocytic membrane antigens of P. falciparum-infected erythro

Details Erythrocytic membrane antigens of P. falciparum-infected erythro Erythrocytic membrane antigens of P. falciparum-infected erythro

1988-04-14

1991-05-28

Moskowitz, Margaret

Chemistry: molecular biology and microbiology

Spore forming or isolating process

530387, 530809, C12N 500, A61K 3514, C07K 300, C07K 1300

Patent

active

050195115

ABSTRACT:
Monoclonal antibodies are disclosed that react with an antigenic polypeptide having a molecular weight of approximately 45,000 that is expressed in the cell membrane of P. falciparun-infected erythrocytes. The antibodies were raised using the Honduras CDC isolate, and can be used for diagnostic purposes. The hybridoma producing the monoclonal antibodies is also disclosed.

REFERENCES:
patent: 4632909 (1986-12-01), Carter
Oldrink et al, FEBS 1984, p. 108 vol. 173.
Lyon et al, PNAS vol. 83, 1986 pp. 2989-2993.
Holder et al, Nature 317, 1985, pp. 270-273.
Santoro et al, WBC 258, 1983, p. 334.
Stanley et al., Proc. Natl. Acad. Sci. USA, 83:6093-6097 (1986). ,
Howard et al,, Mol. Biochem. Parasitol., 17:61-77 (1985).
Stanley et al., Mol. Biochem. Parasitol., 36:139-150 (1989).
Howard et al., Gene, 46:197-205 (1986).
E. Nardin et al., Nature, 274, 55-57 (1978).
H. Stanley et al., J. Immunol., 134, 3439-3444 (1985).
F. Ardeshir et al., Proc. Nat'l Acad. Sci., 82, 2518-2522 (1985).
W. Trager et al., Bull. World Health Org., 35, 883-885 (1966).
S. G. Langreth et al., J. Exp. Med., 150, 1241-1254 (1979).
H. A. Stanley et al., J. Molec. Immunol., 21, 145-150 (1984).
H. A. Stanley et al., Am. J. Trop. Med. Hyg., 33, 12-16 (1984).
I. J. Udeinya et al., Nature, 303, 429-431 (1983).
A. Kilejian, Proc. Nat'l Acad. Sci. USA, 76, 4650-4653 (1979).
A. Kilejian, J. Exp. Med., 151, 1534-1538 (1980).
R. L. Coppel et al., Nature, 310, 789-792 (1984).
H. Perlmann et al., J. Exp. Med., 159, 1686-1704 (1984).
G. V. Brown et al., J. Exp. Med., 162, 774-779 (1985).
J. Gruenberg et al., Proc. Nat'l Acad. Sci. USA, 80, 1087-1091 (1983).
J. H. Leech et al., J. Exp. Med., 159, 1567-1575 (1984).
S. B. Aley et al, J. Exp. Med., 160, 1585-1590 (1984).
S. B. Aley et al., Parasitology, 92, 511-525 (1986).
B. S. Jacobsen et al., Science, 195, 302-304 (1977).
Holder and Freeman, J. Exp. Med., 160, 624-629 (1984).
Simmons et al., EMBO J., 6, 485-491 (1987).
H. Stanley et al., J. Immunol., 134, 3439-3444 (1985).
Vermuillen, A. N. et al, 1985, Develop. Biolog. Standard, vol. 62, pp. 91-97, "Plasmodium falciparum Transmission Blocking . . . ".
Vermeullen, A. N. et al, 1985, J. Exp. Med. 162:1460-1476, "Sequential Expression of Antigens on Sexual Stages of Plasmodium . . . ".

Affiliated with

Also associated with

Rating

Erythrocytic membrane antigens of P. falciparum-infected erythro does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Erythrocytic membrane antigens of P. falciparum-infected erythro, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Erythrocytic membrane antigens of P. falciparum-infected erythro will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-35725