Chemistry: analytical and immunological testing – Involving immune complex formed in liquid phase – Separation of immune complex from unbound antigen or antibody
Patent
1989-03-16
1992-02-04
Warden, Robert J.
Chemistry: analytical and immunological testing
Involving immune complex formed in liquid phase
Separation of immune complex from unbound antigen or antibody
436501, 436519, 422 61, 530387, G01N 33541
Patent
active
050860020
ABSTRACT:
In a novel, erythrocyte agglutination assay, the agglutination reagent comprises at least one erythrocyte binding molecule coupled to at least one specific analyte binding molecule wherein the erythrocyte binding molecule does not cause agglutination when incubated with erythrocytes in the absence of analyte (in the case of a direct assay) or analyte binding reagent (in the case of an indirect assay). Preferably, the erythrocytes are endogenous to the blood sample to be tested, that is, a whole blood sample is assayed. Mixtures of conjugates and conjugates of analyte analogues with erythrocyte binding molecules may also be used as agglutination reagents. The reagents and their use in direct or indirect assays is disclosed.
REFERENCES:
patent: 4130634 (1978-12-01), Molinaro
patent: 4401764 (1983-08-01), Smith
patent: 4433059 (1984-02-01), Chang et al.
patent: 4493793 (1985-01-01), Chu
patent: 4517303 (1985-03-01), Freytag
patent: 4578360 (1986-03-01), Smith
patent: 4590169 (1986-05-01), Cragle
patent: 4594327 (1986-06-01), Zuk
patent: 4661444 (1981-04-01), Li
patent: 4668637 (1981-03-01), Guesdon
patent: 4676980 (1981-06-01), Segal
patent: 4695553 (1987-09-01), Wardlaw
patent: 4829011 (1989-05-01), Gibbons
patent: 4900685 (1990-02-01), Smith, III
Bundesen Peter G.
Hillyard Carmel J.
Kemp Bruce E.
Rylatt Dennis B.
Agen Biomedical Ltd.
Alexander Lyle
Cooper Iver P.
Warden Robert J.
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