Ergot peptide derivatives, their preparation and pharmaceutical

Details Ergot peptide derivatives, their preparation and pharmaceutical Ergot peptide derivatives, their preparation and pharmaceutical

1983-05-10

1985-10-15

Rollins, Alton D.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Heterocyclic carbon compounds containing a hetero ring...

544346, 546 69, A61K 3148, A61K 31495, C07D51902

Patent

active

045475008

ABSTRACT:
A 2-methyl-8 (R) or (S) ergot peptide alkaloid in free base form or in pharmaceutically acceptable acid addition salt form is a useful anti-Parkinson agent, prolactin secretion inhibitor, anti-depressant, vigilance-increasing agent, and anti-migraine agent.

REFERENCES:
patent: 3752814 (1973-08-01), Fluckiger et al.
patent: 3901891 (1975-08-01), Fehr et al.
patent: 4091099 (1978-05-01), Fehr et al.
patent: 4321381 (1982-03-01), Mantegani et al.
Bernardi et al., La Chimica e L'Industria, vol. 54, pp. 998-999 (1972).
Berde et al., ed., Ergot Alkaloids and Related Compounds, (Springer-Verlag, New York, 1978), pp. 1-5, 40-44 and 69-73.

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