Ergoline derivatives of 1-propinylamine, a process for the manuf

Details Ergoline derivatives of 1-propinylamine, a process for the manuf Ergoline derivatives of 1-propinylamine, a process for the manuf

1993-12-02

1996-01-02

Lovering, Richard D.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

546 67, 546 69, A61K 3144

Patent

active

054808855

ABSTRACT:
A method of treating psychosis including administering an antipsychotically effective amount of an ergolinyl derivative of 2-propinylamine of the formula I ##STR1## wherein, R.sub.1, R.sub.2, and R.sub.3 independently represent a hydrogen atom or a straight-chain or branched-chain C.sub.1 -C.sub.6 alkyl group, X represents a hydrogen or a halogen atom, Z represents a carbonyl or methylene group, and C.sub.9 - - - -C.sub.10 represents a single or a double, diastereomeric forms, racemates and acid addition salts thereof.

REFERENCES:
patent: 3228944 (1966-01-01), Bernardi
patent: 3346580 (1967-10-01), Hofmann et al.
patent: 4064249 (1977-12-01), Mago

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