Ergoline carboxamides

Details Ergoline carboxamides Ergoline carboxamides

1983-04-13

1986-12-30

Hendricks, Glenna M.

Organic compounds -- part of the class 532-570 series

Organic compounds

Nitrogen attached directly or indirectly to the purine ring...

544310, 544317, 544318, 544319, 546 67, 546 69, A61K 3148, B07D45706, C07D23942

Patent

active

046329900

ABSTRACT:
There are provided ergoline derivatives of the formula: ##STR1## wherein R.sub.1 represents a hydrogen atom or a methyl group, R.sub.2 represents a hydrogen or halogen atom or a methyl group, R.sub.3 represents a hydrogen atom or a methoxy group, R.sub.4 represents a hydrocarbon group having from 1 to 4 carbon atoms; each of X and W independently represents a hydrogen atom, a methyl group, a chlorine atom or a methoxy group, and n is 0, 1 or 2. A method for their preparation is also provided. The compounds have strong antiprolactin activity.

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patent: 4291031 (1981-09-01), Takaya et al.
Guyton, Arthur C., Medical Physiology, 6th, W. B. Saunders, Philadelphia, 1981.

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