ErbB receptor-derived peptide fragments

Chemistry: natural resins or derivatives; peptides or proteins; – Peptides of 3 to 100 amino acid residues – 15 to 23 amino acid residues in defined sequence

Reexamination Certificate

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C530S300000, C514S001100, C514S007600, C514S021400

Reexamination Certificate

active

07897723

ABSTRACT:
The invention relates to new peptide compounds capable of modulating cell proliferation, differentiation, survival and/or motility. The peptide compounds of the invention comprise short peptide fragments of the ErbB receptor and are capable of binding to ErbB and modulating activity of the receptor. The invention also relates to antibodies capable of binding to an epitope comprising a peptide sequence of the invention, pharmaceutical compositions comprising the peptide sequences and/or antibodies and uses thereof for treatment of conditions wherein modulating activity of ErbB is needed.

REFERENCES:
patent: 1479693 (2004-11-01), None
patent: WO 01/08636 (2001-02-01), None
patent: WO 2006/026569 (2006-03-01), None
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