Equine strangles vaccine and the method of preparing and using t

Details Equine strangles vaccine and the method of preparing and using t Equine strangles vaccine and the method of preparing and using t

1985-07-15

1988-11-29

Wiseman, Thomas G.

Drug, bio-affecting and body treating compositions

Whole live micro-organism, cell, or virus containing

Genetically modified micro-organism, cell, or virus

424 88, 424 92, 4351721, 435253, 435885, A61K 3900, A61K 3700, C12N 1500, C12N 120

Patent

active

047880597

ABSTRACT:
A vaccine for immunizing equines against strangles and a method of using the vaccine. The vaccine is made by isolating the causative organism Streptococcus equi (S. equi) from an abscess on a horse showing typical symptoms of strangles, and confirming the identity of the organism through standard biochemical techniques. The isolated S. equi is passed through a suitable growth medium (Todd-Hewitt broth) and two parts per million acriflavine hydrochloride is added. The acriflavine level is increased over a period of approximately eleven weeks to a concentration of about sixteen parts per million to yield an avirulent S. equi while retaining its antigenicity. The method of administering the vaccine consists of inoculating the horse intranasally with the attenuated S. equi.

REFERENCES:
patent: 3529056 (1970-09-01), Engelbrecht
patent: 3793150 (1974-02-01), Usdin
patent: 3852420 (1974-12-01), Usdin
patent: 4328210 (1982-05-01), Kucera
patent: 4335106 (1982-06-01), Kucera
patent: 4626430 (1986-12-01), Kucera
patent: 4681762 (1987-07-01), Oeschger et al.
Manual Methods General Bacteriology (Eds. P. Gerhardt et al) Amer. Soc. Microbiol., Wash. D.C., 1981 p. 226.
Timoney et al Chem Abst vol. 106(20) No. 162558x 1987, "Vaccine for the Protection of Equines Against Streptococcus equi".
"The Production of Filtering Forms of Streptococcus equi and the Study of Regenerated Cultures", Zhalobovskiy, publ. at Tr. Inst. Vet. Kazakhsk. Filiala Vses. Aka. Selskokhoz. Nauk Im. V. I. Lenina 8.201-209. 1957; Referat. Zhur., Biol., 1959, No. 91687 (English translation included).

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