Drug – bio-affecting and body treating compositions – Antigen – epitope – or other immunospecific immunoeffector – Recombinant virus encoding one or more heterologous proteins...
Patent
1993-09-21
1996-01-09
Mosher, Mary E.
Drug, bio-affecting and body treating compositions
Antigen, epitope, or other immunospecific immunoeffector
Recombinant virus encoding one or more heterologous proteins...
4241861, 4242291, 935 65, 4352351, A61K 39285, A61K 39275, A61K 39245, A61K 3927
Patent
active
054827132
ABSTRACT:
What is described is a recombinant poxvirus, such as vaccinia virus, fowlpox virus and canarypox virus, containing foreign DNA from herpesvirus. In one embodiment, the foreign DNA is expressed in a host by the production of a herpesvirus glycoprotein. In another embodiment, the foreign DNA is expressed in a host by the production of at least two, particularly two or three, herpesvirus glycoproteins. What is also described is a vaccine containing the recombinant poxvirus for inducing an immunological response in a host animal inoculated with the vaccine. By the present invention, the barrier of maternal immunity in a newborn offspring can be overcome or avoided.
REFERENCES:
patent: 5242829 (1993-09-01), Panicali et al.
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Van Drunen-Littel-van den Hurk et al., 1989, J. Virol. vol. 63, pp. 2159-2168.
Whalley, J. M. et al. 1989, J. Gen. Virol. vol. 70 pp. 383-394.
Riggio, M. P. et al. 1989, J. Virol. vol. 63 pp. 1123-1133.
Taylor, J. et al. 1988, Vaccine vol. 6 pp. 497-503.
Allen, G. P. et al., 1987, J. Virol. vol. 61 pp. 2454-2461.
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Piccini, A. et al. 1987, Meth. Enzymol. vol. 153 pp. 545-563.
Health Research Incorporated
Mosher Mary E.
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