Equine herpesvirus-4TK mutant

Details Equine herpesvirus-4TK mutant Equine herpesvirus-4TK mutant

1997-11-07

2000-02-15

Mosher, Mary E.

Chemistry: molecular biology and microbiology

Virus or bacteriophage, except for viral vector or...

4353201, 435325, 4241991, 4242051, 4242291, 424820, C12N 700, C12N 701, C12N 1586

Patent

active

060251816

ABSTRACT:
An Equine herpesvirus-4 (EHV-4) mutant which does not produce a functional thymidine kinase due to a deletion and/or insertion in the gene encoding thymidine kinase, the deletion and/or insertion made at a position within the thymidine kinase gene such as to not substantially alter expression of the UL24 gene. Recombinant DNA comprising DNA of the EHV-4 mutant, host cells containing the recombinant DNA, and a process for the preparation of the EHV-4 mutant.

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