Equine GM-CSF

Details Equine GM-CSF Equine GM-CSF

2007-07-31

2007-07-31

Spector, Lorraine (Department: 1647)

Drug, bio-affecting and body treating compositions

Lymphokine

C424S192100, C424S198100, C435S069500, C435S069700, C530S351000, C530S399000

Reexamination Certificate

active

10614481

ABSTRACT:
Disclosed and/or claimed is subject matter including: equine GM-CSF, its amino acid sequence, nucleic acid molecules encoding equine GM-CSF, use of equine GM-CSF as an adjuvant or non-specific immunity stimulant, compositions containing equine GM-CSF and vectors expressing GM-CSF.

REFERENCES:
patent: 5162111 (1992-11-01), Grabstein et al.
patent: 5980911 (1999-11-01), Corner et al.
patent: WO 92/05255 (1992-04-01), None
patent: WO 94/01133 (1994-01-01), None
patent: WO 98/03198 (1998-01-01), None
UniProt search results for SEQ ID No. 9, executedMay 31, 2006.
S.A. Hammond et al., “Functional characterization of equine dendriti cells propagated ex vivo using recombinant human GM-CSF and recombinant equine IL-4”, Vet. Immunol. and Immunopath. 71:197-214, 1999.
Database EMBL 'en ligne! CE 14392, accession No. U14392, Sep. 14, 1994 E.A Lockhart: “Cloning and sequencing of cerine GM-CSF”, referred to as XP 0021488166.
McInnes, C.J. et al., “Cloning and expression of a cDNA encoding ovine granulocyte-macrophage colony-stimulating factor”, Gene, 1991, vol. 105, No. 2, pp. 275-279.
Inumaru, S. et al., “cDNA cloning of porcine granulocyte-macrophage colony-stimulating factor”, Immunology and Cell Biology, 1995, vol. 73, No. 5, pp. 474-476.
Sin, J., et al., “Protective immunity against heterologous challenge with encephalomyocarditis virus by VP1 DNA vaccination: effect of coinjection with a granulocyte-macrophage colony stimulating factor gene”, Vaccine, 1997, vol. 15, No. 17/18 pp. 1827-1833.
Hartikka, J., et al., “An improved Plasmid DNA Expression Vector for Direct Injection into Skeletal Muscle”, Human Gene Therapy, 1996, vol. 7, No. 10 pp. 1205-1217.

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